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Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors

Anpilov, Sergey ; Shemesh, Yair ; Eren, Noa ; Harony-Nicolas, Hala ; Benjamin, Asaf ; Dine, Julien ; Oliveira, Vinícius Elias de Moura ; Forkosh, Oren ; Karamihalev, Stoyo ; Hüttl, Rosa-Eva ; Feldman, Noa ; Berger, Ryan ; Dagan, Avi ; Chen, Gal ; Neumann, Inga D. ; Wagner, Shlomo ; Yizhar, Ofer ; Chen, Alon



Abstract

Complex behavioral phenotyping techniques are becoming more prevalent in the field of behavioral neuroscience, and thus methods for manipulating neuronal activity must be adapted to fit into such paradigms. Here, we present a head-mounted, magnetically activated device for wireless optogenetic manipulation that is compact, simple to construct, and suitable for use in group-living mice in an ...

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