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In Vitro and In Vivo Biocompatibility Studies of a Cast and Coated Titanium Alloy

Sommer, Ursula ; Laurich, Stephan ; de Azevedo, Lucie ; Viehoff, Katharina ; Wenisch, Sabine ; Thormann, Ulrich ; Alt, Volker ; Heiss, Christian ; Schnettler, Reinhard



Zusammenfassung

The biocompatibility of a cast porous and with a calcium titanate reaction layer functionalized titanium alloy (Ti-6Al-7Nb) was tested by means of cell culture, and a small (rat) and large animal (sheep) model. The uncoated titanium material served as a control. In-vitro tests included the validation of osteoblast-like cells attached to the surface of the material with scanning electron ...

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