Go to content
UR Home

CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect

Reil, Jan‐Christian ; Reil, Gert‐Hinrich ; Kovács, Árpád ; Sequeira, Vasco ; Waddingham, Mark T. ; Lodi, Maria ; Herwig, Melissa ; Ghaderi, Shahrooz ; Kreusser, Michael M. ; Papp, Zoltán ; Voigt, Niels ; Dobrev, Dobromir ; Meyhöfer, Svenja ; Langer, Harald F. ; Maier, Lars S. ; Linz, Dominik ; Mügge, Andreas ; Hohl, Mathias ; Steendijk, Paul ; Hamdani, Nazha



Abstract

Key points The Anrep effect represents the alteration of left ventricular (LV) contractility to acutely enhanced afterload in a few seconds, thereby preserving stroke volume (SV) at constant preload. As a result of the missing preload stretch in our model, the Anrep effect differs from the slow force response and has a different mechanism. The Anrep effect demonstrated two different phases. ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons