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Cholangiocarcinoma 2020: the next horizon in mechanisms and management

Banales, Jesus M. ; Marin, Jose J. G. ; Lamarca, Angela ; Rodrigues, Pedro M. ; Khan, Shahid A. ; Roberts, Lewis R. ; Cardinale, Vincenzo ; Carpino, Guido ; Andersen, Jesper B. ; Braconi, Chiara ; Calvisi, Diego F. ; Perugorria, Maria J. ; Fabris, Luca ; Boulter, Luke ; Macias, Rocio I. R. ; Gaudio, Eugenio ; Alvaro, Domenico ; Gradilone, Sergio A. ; Strazzabosco, Mario ; Marzioni, Marco ; Coulouarn, Cédric ; Fouassier, Laura ; Raggi, Chiara ; Invernizzi, Pietro ; Mertens, Joachim C. ; Moncsek, Anja ; Rizvi, Sumera ; Heimbach, Julie ; Koerkamp, Bas Groot ; Bruix, Jordi ; Forner, Alejandro ; Bridgewater, John ; Valle, Juan W. ; Gores, Gregory J.



Zusammenfassung

Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence is increasing globally, currently accounting for similar to 15% of all primary liver cancers and similar to 3% of gastrointestinal malignancies. The silent presentation of these tumours combined with their highly aggressive nature and ...

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