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Randomised trial on performance, safety and clinical benefit of hyaluronic acid, hyaluronic acid plus dexpanthenol and isotonic saline nasal sprays in patients suffering from dry nose symptoms

Thieme, Uta ; Müller, Karolina ; Bergmann, Christoph ; Bock, Bernward ; Wurzer-Materna, Nadine ; Shahab, Taufik ; Zeman, Florian ; Eberhardt, Yvonne ; Huppertz, Gunnar ; Koller, Michael ; Meiser, Peter



Abstract

Objective: Limited data exist on the clinical benefits of nasal applications for moistening the nasal mucosa. We therefore investigated the effects of hyaluronic acid, hyaluronic acid plus dexpanthenol and isotonic saline nasal sprays in patients suffering from dry nose symptoms in an otorhinolaryngological outpatient setting. Methods: 240 patients were randomised into this prospective, ...

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