Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL
Hubmann, Rainer
, Schnabl, Susanne, Araghi, Mohammad, Schmidl, Christian
, Rendeiro, André F., Hilgarth, Martin, Demirtas, Dita, Ali, Farghaly
, Staber, Philipp B., Valent, Peter
, Zielinski, Christoph, Jäger, Ulrich and Shehata, Medhat
(2020)
Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL.
Cells 9 (6), p. 1484.
Date of publication of this fulltext: 11 Oct 2021 12:47
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| Item type | Article | ||||
| Journal or Publication Title | Cells | ||||
| Publisher: | MDPI | ||||
|---|---|---|---|---|---|
| Place of Publication: | BASEL | ||||
| Volume: | 9 | ||||
| Number of Issue or Book Chapter: | 6 | ||||
| Page Range: | p. 1484 | ||||
| Date | 2020 | ||||
| Institutions | Leibniz Institute for Immunotherapy (LIT) | ||||
| Identification Number |
| ||||
| Keywords | LYMPHOCYTIC-LEUKEMIA CLL; KINASE-C-DELTA; B-CLL; APOPTOSIS; EXPRESSION; INHIBITOR; CANCER; CELLS; TRANSCRIPTION; ACTIVATION; chronic lymphocytic leukemia (CLL); NOTCH2; NOTCH3; FCER2 (CD23); NR4A1; gliotoxin; RO4929097; gamma-secretase inhibitors; ATAC-seq; binary cell fate decision; positive/negative selection; CD5+B-cell homeostasis | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 49965 |
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