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Critical Role of Transcript Cleavage in Arabidopsis RNA Polymerase II Transcriptional Elongation

Antosz, Wojciech ; Deforges, Jules ; Begcy, Kevin ; Bruckmann, Astrid ; Poirier, Yves ; Dresselhaus, Thomas ; Grasser, Klaus D.


Transcript elongation factors associate with elongating RNA polymerase II (RNAPII) to control the efficiency of mRNA synthesis and consequently modulate plant growth and development. Encountering obstacles during transcription such as nucleosomes or particular DNA sequences may cause backtracking and transcriptional arrest of RNAPII. The elongation factor TFIIS stimulates the intrinsic transcript ...


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