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Technical Validation of an Automated Mobile Gait Analysis System for Hereditary Spastic Paraplegia Patients

Martindale, Christine F. ; Roth, Nils ; Gassner, Heiko ; List, Julia ; Regensburger, Martin ; Eskofier, Bjoern M. ; Kohl, Zacharias



Abstract

Hereditary spastic paraplegias (HSP) represents a group of orphan neurodegenerative diseases with gait disturbance as the predominant clinical feature. Due to its rarity, research within this field is still limited. Aside from clinical analysis using established scales, gait analysis has been employed to enhance the understanding of the mechanisms behind the disease. However, state of the art ...

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