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Transcorneal Electrical Stimulation for the Treatment of Retinitis Pigmentosa: A Multicenter Safety Study of the OkuStim® System (TESOLA-Study)

Jolly, Jasleen K. ; Wagner, Siegfried K. ; Martus, Peter ; MacLaren, Robert E. ; Wilhelm, Barbara ; Webster, Andrew R. ; Downes, Susan M. ; Charbel Issa, Peter ; Kellner, Ulrich ; Jägle, Herbert ; Rüther, Klaus ; Bertelsen, Mette ; Bragadóttir, Ragnheiður ; Prener Holtan, Josephine ; van den Born, L. Ingeborgh ; Sodi, Andrea ; Virgili, Gianni ; Gosheva, Mariya ; Pach, Johanna ; Zündorf, Ida ; Zrenner, Eberhart ; Gekeler, Florian


Background: Transcorneal electrical stimulation (TES) has been suggested as a possible treatment for retinitis pigmentosa (RP). Objective: To expand the safety assessment of repeated applications of an electrical current from a DTL-like electrode in patients with RP. Methods: This single-arm open label interventional safety trial included a total of 105 RP patients from 11 European centers, who ...


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