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Myeloid-Derived Suppressor Cells in Kidney Transplant Recipients and the Effect of Maintenance Immunotherapy

Iglesias-Escudero, María ; Sansegundo-Arribas, David ; Riquelme, Paloma ; Merino-Fernández, David ; Guiral-Foz, Sandra ; Pérez, Carmen ; Valero, Rosalia ; Ruiz, Juan Carlos ; Rodrigo, Emilio ; Lamadrid-Perojo, Patricia ; Hutchinson, James A. ; Ochando, Jordi ; López-Hoyos, Marcos



Zusammenfassung

Myeloid-derived suppressor cells (MDSC) represent a heterogeneous group of myeloid regulatory cells that were originally described in cancer. Several studies in animal models point to MDSC as important players in the induction of allograft tolerance due to their immune modulatory function. Most of the published studies have been performed in animal models, and the data addressing MDSCs in human ...

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