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High Expression of RING Finger Protein 126 Predicts Unfavorable Prognosis of Epithelial Ovarian Cancer

Wang, Chuanjiang ; Wen, Aiping ; Qiao, Jing ; Liu, Yujuan ; Guo, Yuanyuan ; Wang, Wenxia



Abstract

Background: Ovarian cancer (OC) is one of the leading causes of cancer-related mortality worldwide. The clinical outcome of EOC remains unsatisfactory with current therapeutic approaches such as surgery and platinum/taxane-based chemotherapy. Therefore, novel prognostic markers and personalized therapies targeting specific molecules are urgently needed. Here, we explored whether RNF126, an E3 ...

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