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Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy

Ritschl, Paul V. ; Hofhansel, Lena ; Flörchinger, Bernhard ; Oberhuber, Rupert ; Öllinger, Robert ; Pratschke, Johann ; Kotsch, Katja


While both living donation and donation after circulatory death provide alternative opportunities for organ transplantation, donation after donor brain death (BD) still represents the major source for solid transplants. Unfortunately, the irreversible loss of brain function is known to induce multiple pathophysiological changes, including hemodynamic as well as hormonal modifications, finally ...


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