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Childhood asthma in the new omics era: challenges and perspectives

Golebski, Korneliusz ; Kabesch, Michael ; Melén, Erik ; Potočnik, Uroš ; van Drunen, Cornelis M. ; Reinarts, Susanne ; Maitland-van der Zee, Anke H. ; Vijverberg, Susanne J.H.



Abstract

Purpose of review Childhood asthma is a heterogeneous inflammatory disease comprising different phenotypes and endotypes and, particularly in its severe forms, has a large impact on the quality-of-life of patients and caregivers. The application of advanced omics technologies provides useful insights into underlying asthma endotypes and may provide potential clinical biomarkers to guide treatment ...

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