Benchmarking of survival outcomes following haematopoietic stem cell transplantation: A review of existing processes and the introduction of an international system from the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE)

Snowden, John A. ; Saccardi, Riccardo ; Orchard, Kim ; Ljungman, Per ; Duarte, Rafael F. ; Labopin, Myriam ; McGrath, Eoin ; Brook, Nigel ; de Elvira, Carmen Ruiz ; Gordon, Debra ; Poirel, Hélène A. ; Ayuk, Francis ; Beguin, Yves ; Bonifazi, Francesca ; Gratwohl, Alois ; Milpied, Noel ; Moore, John ; Passweg, Jakob ; Rizzo, J. Douglas ; Spellman, Stephen R. ; Sierra, Jorge ; Solano, Carlos ; Sanchez-Guijo, Fermin ; Worel, Nina ; Gusi, Andreu ; Adams, Gillian ; Balan, Theodor ; Baldomero, Helen ; Macq, Gilles ; Marry, Evelyne ; Mesnil, Florence ; Oldani, Elena ; Pearce, Rachel ; Perry, Julia ; Raus, Nicole ; Schanz, Urs ; Tran, Steven ; Wilcox, Leonie ; Basak, Grzegorz W. ; Chabannon, Christian ; Corbacioglu, Selim ; Dolstra, Harry ; Kuball, Jürgen ; Mohty, Mohamad ; Lankester, Arjan ; Montoto, Sylvia ; Nagler, Arnon ; Styczynski, Jan ; Yakoub-Agha, Ibrahim ; de Latour, Regis Peffault ; Kroeger, Nicolaus ; Brand, Ronald ; de Wreede, Liesbeth C. ; van Zwet, Erik ; Putter, Hein

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Alternative Links zum Volltext:DOIVerlag

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Details

Dokumentenart:	Artikel
Titel eines Journals oder einer Zeitschrift:	Bone Marrow Transplantation
Verlag:	Nature
Ort der Veröffentlichung:	LONDON
Band:	55
Nummer des Zeitschriftenheftes oder des Kapitels:	4
Seitenbereich:	S. 681-694
Datum:	2020
Institutionen:	Medizin > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation
Identifikationsnummer:	Wert Typ 10.1038/s41409-019-0718-7 DOI
Stichwörter / Keywords:	CLINICAL-OUTCOMES; SURGERY; UNIT;
Dewey-Dezimal-Klassifikation:	600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
Status:	Veröffentlicht
Begutachtet:	Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:	Ja
Dokumenten-ID:	50162

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Zusammenfassung

In many healthcare settings, benchmarking for complex procedures has become a mandatory requirement by competent authorities, regulators, payers and patients to assure clinical performance, cost-effectiveness and safe care of patients. In several countries inside and outside Europe, benchmarking systems have been established for haematopoietic stem cell transplantation (HSCT), but access is not ...

Zusammenfassung

In many healthcare settings, benchmarking for complex procedures has become a mandatory requirement by competent authorities, regulators, payers and patients to assure clinical performance, cost-effectiveness and safe care of patients. In several countries inside and outside Europe, benchmarking systems have been established for haematopoietic stem cell transplantation (HSCT), but access is not universal. As benchmarking is now integrated into the FACT-JACIE standards, the EBMT and JACIE established a Clinical Outcomes Group (COG) to develop and introduce a universal system accessible across EBMT members. Established systems from seven European countries (United Kingdom, Italy, Belgium, France, Germany, Spain, Switzerland), USA and Australia were appraised, revealing similarities in process, but wide variations in selection criteria and statistical methods. In tandem, the COG developed the first phase of a bespoke risk-adapted international benchmarking model for one-year survival following allogeneic and autologous HSCT based on current capabilities within the EBMT registry core dataset. Data completeness, which has a critical impact on validity of centre comparisons, is also assessed. Ongoing development will include further scientific validation of the model, incorporation of further variables (when appropriate) alongside implementation of systems for clinically meaningful interpretation and governance aiming to maximise acceptance to centres, clinicians, payers and patients across EBMT.

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