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alpha-Synuclein: a Modulator During Inflammatory CNS Demyelination

Kuhbandner, Kristina ; Hoffmann, Alana ; González Alvarado, María Nazareth ; Seyler, Lisa ; Bäuerle, Tobias ; Winkler, Jürgen ; Linker, Ralf A.



Abstract

Neuroinflammation and demyelination are hallmarks of several neurological disorders such as multiple sclerosis and multiple system atrophy. To better understand the underlying mechanisms of de- and regeneration in respective diseases, it is critical to identify factors modulating these processes. One candidate factor is alpha-Synuclein (aSyn), which is known to be involved in the pathology of ...

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