Duscha, Alexander ; Gisevius, Barbara ; Hirschberg, Sarah ; Yissachar, Nissan ; Stangl, Gabriele I. ; Eilers, Eva ; Bader, Verian ; Haase, Stefanie ; Kaisler, Johannes ; David, Christina ; Schneider, Ruth ; Troisi, Riccardo ; Zent, Daniel ; Hegelmaier, Tobias ; Dokalis, Nikolaos ; Gerstein, Sara ; Del Mare-Roumani, Sara ; Amidror, Sivan ; Staszewski, Ori ; Poschmann, Gereon ; Stühler, Kai ; Hirche, Frank ; Balogh, Andras ; Kempa, Stefan ; Träger, Pascal ; Zaiss, Mario M. ; Holm, Jacob Bak ; Massa, Megan G. ; Nielsen, Henrik Bjørn ; Faissner, Andreas 
; Lukas, Carsten ; Gatermann, Sören G. ; Scholz, Markus ; Przuntek, Horst ; Prinz, Marco ; Forslund, Sofia K. ; Winklhofer, Konstanze F. ; Müller, Dominik N. ; Linker, Ralf A. ; Gold, Ralf ; Haghikia, Aiden
; Lukas, Carsten ; Gatermann, Sören G. ; Scholz, Markus ; Przuntek, Horst ; Prinz, Marco ; Forslund, Sofia K. ; Winklhofer, Konstanze F. ; Müller, Dominik N. ; Linker, Ralf A. ; Gold, Ralf ; Haghikia, Aiden 
Abstract
Short-chain fatty acids are processed from indigestible dietary fibers by gut bacteria and have immunomodulatory properties. Here, we investigate propionic acid (PA) in multiple sclerosis (MS), an autoimmune and neurodegenerative disease. Serum and feces of subjects with MS exhibited significantly reduced PA amounts compared with controls, particularly after the first relapse. In a ...
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