Direkt zum Inhalt

Hedgehog Signaling Modulates Glial Proteostasis and Lifespan

Rallis, Andrew ; Navarro, Juan A. ; Rass, Mathias ; Hu, Amélie ; Birman, Serge ; Schneuwly, Stephan ; Thérond, Pascal P.



Zusammenfassung

The conserved Hedgehog signaling pathway has well-established roles in development. However, its function during adulthood remains largely unknown. Here, we investigated whether the Hedgehog signaling pathway is active during adult life in Drosophila melanogaster, and we uncovered a protective function for Hedgehog signaling in coordinating correct proteostasis in glial cells. Adult-specific ...

plus


Nur für Besitzer und Autoren: Kontrollseite des Eintrags
nach oben