A precisely positioned MED12 activation helix stimulates CDK8 kinase activity
Article
Klatt, Felix, Leitner, Alexander
, Kim, Iana V. , Ho-Xuan, Hung , Schneider, Elisabeth V., Langhammer, Franziska, Weinmann, Robin, Müller, Melanie R., Huber, Robert, Meister, Gunter and Kuhn, Claus-D.
(2020)
A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.
Proceedings of the National Academy of Sciences 117 (6), pp. 2894-2905.
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| Item type | Article | ||||
| Journal or Publication Title | Proceedings of the National Academy of Sciences | ||||
| Publisher | NATL ACAD SCIENCES | ||||
| Place of Publication | WASHINGTON | ||||
| Volume | 117 | ||||
| Number of Issue or Book Chapter | 6 | ||||
| Page Range | pp. 2894-2905 | ||||
| Date | 2020 | ||||
| Date of publication | 11 Oct 2021 13:02 | ||||
| Institutions | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Gunter Meister | ||||
| Identification Number |
| ||||
| Keywords | TRANSCRIPTIONAL ACTIVATION; MASS-SPECTROMETRY; MEDIATOR COMPLEX; CROSS-LINKING; CANCER; MUTATIONS; MODULE; GENE; ASSOCIATION; SUBCOMPLEX; CDK8; MED12; Mediator kinase module; Mediator; kinase inhibitors | ||||
| Dewey Decimal Classification | 500 Science > 570 Life sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 50322 |
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