Aziz, Mina D. ; Shah, Jay ; Kapoor, Urvi ; Dimopoulos, Christina ; Anand, Sarah ; Augustine, Allan ; Ayuk, Francis ; Chaudhry, Mohammed ; Chen, Yi-Bin ; Choe, Hannah K. ; Etra, Aaron ; Gergoudis, Stephanie ; Hartwell, Matthew J. 
; Hexner, Elizabeth O. ; Hogan, William J. ; Kitko, Carrie L. ; Kowalyk, Steven ; Kröger, Nicolaus ; Merli, Pietro ; Morales, George ; Nakamura, Ryotaro ; Ordemann, Rainer ; Pulsipher, Michael A. ; Qayed, Muna ; Reshef, Ran ; Rösler, Wolf ; Schechter, Tal ; Schreiner, Elisabeth ; Srinagesh, Hrishikesh ; Wölfl, Matthias ; Wudhikarn, Kitsada ; Yanik, Gregory ; Young, Rachel ; Özbek, Umut ; Ferrara, James L. M. ; Levine, John E.
; Hexner, Elizabeth O. ; Hogan, William J. ; Kitko, Carrie L. ; Kowalyk, Steven ; Kröger, Nicolaus ; Merli, Pietro ; Morales, George ; Nakamura, Ryotaro ; Ordemann, Rainer ; Pulsipher, Michael A. ; Qayed, Muna ; Reshef, Ran ; Rösler, Wolf ; Schechter, Tal ; Schreiner, Elisabeth ; Srinagesh, Hrishikesh ; Wölfl, Matthias ; Wudhikarn, Kitsada ; Yanik, Gregory ; Young, Rachel ; Özbek, Umut ; Ferrara, James L. M. ; Levine, John E. 
Abstract
The graft-versus-leukemia (GVL) effect after allogeneic hematopoietic cell transplant (HCT) can prevent relapse but the risk of severe graft-versus-host disease (GVHD) leads to prolonged intensive immunosuppression and possible blunting of the GVL effect. Strategies to reduce immunosuppression in order to prevent relapse have been offset by increases in severe GVHD and nonrelapse mortality (NRM). ...
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