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Ex vivo excimer laser ablation of cornea guttata and ROCK inhibitor‐aided endothelial recolonization of ablated central cornea

Kassumeh, Stefan ; Studnitz, Annabel ; Priglinger, Siegfried G. ; Fuchshofer, Rudolf ; Luft, Nikolaus ; Moloney, Gregory ; Dirisamer, Martin ; Ohlmann, Andreas


Purpose To determine whether excimer laser ablation of guttae is a viable strategy for removal of diseased tissue in Fuchs' endothelial corneal dystrophy (FECD) on excised human Descemet membranes and whether an excimer laser-created wound on healthy human corneas ex vivo is recolonized with corneal endothelial cells. Methods Descemet membranes of FECD patients and corneal endothelium of normal ...


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