Selective PRMT5 Inhibitors Suppress Human CD8+ T Cells by Upregulation of p53 and Impairment of the AKT Pathway Similar to the Tumor Metabolite MTA
Article
Strobl, Carolin Dorothea
, Schaffer, Stefanie, Haug, Tabea, Völkl, Simon, Peter, Katrin, Singer, Katrin, Böttcher, Martin, Mougiakakos, Dimitrios, Mackensen, Andreas
and Aigner, Michael
(2019)
Selective PRMT5 Inhibitors Suppress Human CD8+ T Cells by Upregulation of p53 and Impairment of the AKT Pathway Similar to the Tumor Metabolite MTA.
Molecular Cancer Therapeutics 19 (2), pp. 409-419.
Alternative links to fulltext
Involved Institutions
Details
| Item type | Article | ||||
| Journal or Publication Title | Molecular Cancer Therapeutics | ||||
| Publisher | AMER ASSOC CANCER RESEARCH | ||||
| Place of Publication | PHILADELPHIA | ||||
| Volume | 19 | ||||
| Number of Issue or Book Chapter | 2 | ||||
| Page Range | pp. 409-419 | ||||
| Date | 2019 | ||||
| Date of publication | 11 Oct 2021 13:04 | ||||
| Institutions | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) | ||||
| Identification Number |
| ||||
| Keywords | ARGININE METHYLTRANSFERASE 5; PRE-MESSENGER-RNA; METHYLTHIOADENOSINE PHOSPHORYLASE; LUNG-CANCER; METHYLATION; PROGRESSION; GENE; DIFFERENTIATION; IDENTIFICATION; VULNERABILITY; | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 50373 |
Export bibliographical data
Owner only: item control page
Altmetric
Altmetric