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Strobl, Carolin Dorothea ; Schaffer, Stefanie ; Haug, Tabea ; Völkl, Simon ; Peter, Katrin ; Singer, Katrin ; Böttcher, Martin ; Mougiakakos, Dimitrios ; Mackensen, Andreas ; Aigner, Michael

Selective PRMT5 Inhibitors Suppress Human CD8+ T Cells by Upregulation of p53 and Impairment of the AKT Pathway Similar to the Tumor Metabolite MTA

Article

Strobl, Carolin Dorothea , Schaffer, Stefanie, Haug, Tabea, Völkl, Simon, Peter, Katrin, Singer, Katrin, Böttcher, Martin, Mougiakakos, Dimitrios, Mackensen, Andreas and Aigner, Michael (2019) Selective PRMT5 Inhibitors Suppress Human CD8+ T Cells by Upregulation of p53 and Impairment of the AKT Pathway Similar to the Tumor Metabolite MTA. Molecular Cancer Therapeutics 19 (2), pp. 409-419.



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Details

Item typeArticle
Journal or Publication TitleMolecular Cancer Therapeutics
PublisherAMER ASSOC CANCER RESEARCH
Place of PublicationPHILADELPHIA
Volume19
Number of Issue or Book Chapter2
Page Rangepp. 409-419
Date2019
Date of publication11 Oct 2021 13:04
InstitutionsMedicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number
ValueType
10.1158/1535-7163.MCT-19-0189DOI
KeywordsARGININE METHYLTRANSFERASE 5; PRE-MESSENGER-RNA; METHYLTHIOADENOSINE PHOSPHORYLASE; LUNG-CANCER; METHYLATION; PROGRESSION; GENE; DIFFERENTIATION; IDENTIFICATION; VULNERABILITY;
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID50373

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