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Potential of Treated Dentin Matrix Xenograft for Dentin-Pulp Tissue Engineering

Bakhtiar, Hengameh ; Mazidi, Amir ; Mohammadi-Asl, Saeed ; Hasannia, Sadegh ; Ellini, Mohammad Reza ; Pezeshki-Modaress, Mohammad ; Ostad, Seyed Naser ; Galler, Kerstin ; Azarpazhooh, Amir ; Kishen, Anil



Abstract

Introduction: This study aims to develop and characterize the regenerative potential of an atelopeptidized treated dentin matrix xenograft using in vitro and in vivo models. Methods: Freshly extracted bovine dentin was pulverized into 250- to 500-mu m particles and demineralized with 17% EDTA for 1, 7, and 13 days. The samples were atelopeptidized with pepsin. The degree of demineralization and ...

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