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Pulp ECM-derived macroporous scaffolds for stimulation of dental-pulp regeneration process

Bakhtiar, Hengameh ; Pezeshki-Modaress, Mohammad ; Kiaipour, Zahra ; Shafiee, Mahdieh ; Ellini, Mohammad Reza ; Mazidi, Amir ; Rajabi, Sarah ; Zamanlui Benisi, Soheila ; Ostad, Seyed Naser ; Galler, Kerstin ; Pakshir, Pardis ; Azarpazhooh, Amir ; Kishen, Anil



Abstract

Objective. Recent studies suggest xenogeneic extracellular matrices as potential regenerative tools in dental pulp regeneration. This study aimed to fabricate and characterize a novel three-dimensional macroporous pulp-derived scaffold that enables the attachment, penetration, proliferation and differentiation of mesenchymal stem cells. Method. Bovine pulp was decellularized and characterized ...

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