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Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement

Mahadeo, Kris M. ; Bajwa, Rajinder ; Abdel-Azim, Hisham ; Lehmann, Leslie E. ; Duncan, Christine ; Zantek, Nicole ; Vittorio, Jennifer ; Angelo, Joseph ; McArthur, Jennifer ; Schadler, Keri ; Chan, Sherwin ; Tewari, Priti ; Khazal, Sajad ; Auletta, Jeffery J. ; Choi, Sung Won ; Shoberu, Basirat ; Kalwak, Krzysztof ; Harden, Avis ; Kebriaei, Partow ; Abe, Jun-ichi ; Li, Shulin ; Moffet, Jerelyn Roberson ; Abraham, Susan ; Tambaro, Francesco Paolo ; Kleinschmidt, Katharina ; Richardson, Paul G. ; Corbacioglu, Selim



Abstract

Sinusoidal obstructive syndrome, also known as hepatic veno-occlusive disease, is a potentially life-threatening complication that occurs in children undergoing haemopoietic stem-cell transplantation (HSCT). Differences in the incidence of genetic predisposition and clinical presentation of sinusoidal obstructive syndrome between children and adults have rendered the historical Baltimore and ...

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