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Use of letermovir in off-label indications: Infectious Diseases Working Party of European Society of Blood and Marrow Transplantation retrospective study

Styczyński, Jan ; Tridello, Gloria ; Xhaard, Alienor ; Medinger, Michael ; Mielke, Stephan ; Taskinen, Mervi ; Blijlevens, Nicole ; Rodriguez, M. Aranzazu Bermudez ; Solano, Carlos ; Nikolousis, Emmanouil ; Biffi, Alessandra ; Groll, Andreas H. ; Junghanss, Christian ; Tsirigotis, Panagiotis ; Lioure, Bruno ; Šrámek, Jiří ; Holler, Ernst ; Galaverna, Federica ; Fagioli, Franca ; Knelange, Nina ; Wendel, Lotus ; Gil, Lidia ; de la Camara, Rafael ; Mikulska, Malgorzata ; Ljungman, Per


Letermovir (LMV) is licensed for prophylaxis of CMV infection in allogeneic hematopoietic cell transplant adult CMV-seropositive patients. Due to its favorable safety profile, LMV brings potential for use in other clinical situations, outside the approved indication. The objective of the study was to analyze the efficacy and safety of the use of LMV in off-label indications in EBMT centers. A ...


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