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Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice

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Ai, Xun ; Hammer, Karin P. ; Mustroph, Julian ; Stauber, Teresa ; Birchmeier, Walter ; Wagner, Stefan ; Maier, Lars S.
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 15 Nov 2021 16:37


Arrhythmogenic right ventricular cardiomyopathy is a hereditary, rare disease with an increased risk for sudden cardiac death. The disease-causing mutations are located within the desmosomal complex and the highest incidence is found in plakophilin2. However, there are other factors playing a role for the disease progression unrelated to the genotype such as inflammation or exercise. Competitive ...


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