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Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice

URN to cite this document:
urn:nbn:de:bvb:355-epub-508487
DOI to cite this document:
10.5283/epub.50848
Ai, Xun ; Hammer, Karin P. ; Mustroph, Julian ; Stauber, Teresa ; Birchmeier, Walter ; Wagner, Stefan ; Maier, Lars S.
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 15 Nov 2021 16:37


Abstract

Arrhythmogenic right ventricular cardiomyopathy is a hereditary, rare disease with an increased risk for sudden cardiac death. The disease-causing mutations are located within the desmosomal complex and the highest incidence is found in plakophilin2. However, there are other factors playing a role for the disease progression unrelated to the genotype such as inflammation or exercise. Competitive ...

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