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Oligodendrocytes regulate the adhesion molecule ICAM ‐1 in neuroinflammation

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González‐Alvarado, María Nazareth ; Aprato, Jessica ; Baumeister, Melissa ; Lippert, Magdalena ; Ekici, Arif B. ; Kirchner, Philipp ; Welz, Tobias ; Hoffmann, Alana ; Winkler, Jürgen ; Wegner, Michael ; Haase, Stefanie ; Linker, Ralf A.
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 01 Dec 2021 06:39

This publication is part of the DEAL contract with Wiley.


Recently, oligodendrocytes (Ol) have been attributed potential immunomodulatory effects. Yet, the exact mode of interaction with pathogenic CNS infiltrating lymphocytes remains unclear. Here, we attempt to dissect mechanisms of Ol modulation during neuroinflammation and characterize the interaction of Ol with pathogenic T cells. RNA expression analysis revealed an upregulation of ...


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