Oligodendrocytes regulate the adhesion molecule ICAM ‐1 in neuroinflammation

URN to cite this document:: urn:nbn:de:bvb:355-epub-510232
DOI to cite this document:: 10.5283/epub.51023

González‐Alvarado, María Nazareth

; Aprato, Jessica ; Baumeister, Melissa ; Lippert, Magdalena ; Ekici, Arif B.

; Kirchner, Philipp

; Welz, Tobias ; Hoffmann, Alana

; Winkler, Jürgen ; Wegner, Michael ; Haase, Stefanie ; Linker, Ralf A.

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Date of publication of this fulltext: 01 Dec 2021 06:39

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Abstract

Recently, oligodendrocytes (Ol) have been attributed potential immunomodulatory effects. Yet, the exact mode of interaction with pathogenic CNS infiltrating lymphocytes remains unclear. Here, we attempt to dissect mechanisms of Ol modulation during neuroinflammation and characterize the interaction of Ol with pathogenic T cells. RNA expression analysis revealed an upregulation of ...