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Isoagglutinin apheresis for ABO-incompatible renal transplantation

Black, A. ; Mack, M. ; Dullinger, K. ; Schmitz, Gerd ; Ahrens, Norbert


Blood group antigens of the ABO-type are expressed with broad tissue distribution, including endothelial, epithelial and red blood cells. This has traditionally restricted solid organ transplantation to major ABO compatibility. We therefore asked, if this barrier could be overcome by isoagglutinin apheresis before transplantation. In four patients on dialysis with ABO incompatible living related ...


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