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Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report

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Walter, Nike ; Mendelsohn, Daniel ; Brochhausen, Christoph ; Rupp, Markus ; Alt, Volker
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Date of publication of this fulltext: 12 Jan 2022 09:55


The pathophysiological role of intracellular bacteria in osteomyelitis is still a matter of debate. Here, we demonstrate for the first time the presence of Staphylococcus aureus internalized into osteoblasts in human tissue samples of a case with a chronic osteomyelitis using ultrastructural transmission electron microscope analysis.

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