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The role of 25-hydroxyvitamin-D3 and vitamin D receptor gene in human periodontal ligament fibroblasts as response to orthodontic compressive strain: an in vitro study

URN to cite this document:
urn:nbn:de:bvb:355-epub-514028
DOI to cite this document:
10.5283/epub.51402
Küchler, Erika Calvano ; Schröder, Agnes ; Teodoro, Vinicius Broska ; Nazet, Ute ; Scariot, Rafaela ; Spanier, Gerrit ; Proff, Peter ; Kirschneck, Christian
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Date of publication of this fulltext: 12 Jan 2022 13:44



Abstract

Background: This study aimed to investigate, if diferent physiological concentrations of vitamin D (25(OH)D3) and single nucleotide polymorphisms in vitamin D receptor (VDR) gene have an impact on gene expression in human periodontal ligament (hPDL) fbroblasts induced by simulated orthodontic compressive strain. Methods: A pool of hPDL fbroblasts was treated in absence or presence of ...

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