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Results of Treatment with Rituximab (Anti-CD20) in Three Patients with Autoimmune Hemolytic Anemia and/or Immune Thrombocytopenia and a Concise Review of Reported Cases

Ahrens, Norbert ; Heymann, G. ; Meyer, O. ; Kiesewetter, H. ; Salama, A.


Rituximab, a human-mouse chimeric monoclonal antibody against the CD20 antigen on B lymphocytes, is increasingly used for treatment of autoimmune diseases. We report on the outcome of rituximab therapy in 1 patient with decompensated idiopathic autoimmune hemolytic anemia (AIHA) and in 2 patients with severe immune thrombocytopenia (ITP) in combination with compensated AIHA (Evans’ syndrome). All ...


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