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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-514639
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.51463
Zusammenfassung
Simple Summary: We investigated the genes DIRAS-1 and DIRAS-2 in terms of their regulation and functional relevance in brain tumors (gliomas). We found that in a majority of patients the expression of both genes is strongly downregulated on the mRNA level when comparing tumors with healthy brain tissue. We could show that epigenetic mechanisms account for this downregulation. Both promoter ...
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