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Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats

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Oliveira, Vinícius Elias de Moura ; Lukas, Michael ; Wolf, Hannah Nora ; Durante, Elisa ; Lorenz, Alexandra ; Mayer, Anna-Lena ; Bludau, Anna ; Bosch, Oliver J. ; Grinevich, Valery ; Egger, Veronica ; de Jong, Trynke R. ; Neumann, Inga D.
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 17 Feb 2022 14:50


In contrast to male rats, aggression in virgin female rats has been rarely studied. Here, we established a rat model of enhanced aggression in females using a combination of social isolation and aggression-training to specifically investigate the involvement of the oxytocin (OXT) and arginine vasopressin (AVP) systems within the lateral septum (LS). Using neuropharmacological, optogenetic, ...


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