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The New Old CD8+ T Cells in the Immune Paradox of Pregnancy

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Hardardottir, Lilja ; Bazzano, Maria Victoria ; Glau, Laura ; Gattinoni, Luca ; Köninger, Angela ; Tolosa, Eva ; Solano, Maria Emilia
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 21 Mar 2022 14:39


CD8+ T cells are the most frequent T cell population in the immune cell compartment at the feto-maternal interface. Due to their cytotoxic potential, the presence of CD8+ T cells in the immune privileged pregnant uterus has raised considerable interest. Here, we review our current understanding of CD8+ T cell biology in the uterus of pregnant women and discuss this knowledge in relation to a ...


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