The New Old CD8+ T Cells in the Immune Paradox of Pregnancy

URN to cite this document:: urn:nbn:de:bvb:355-epub-519607
DOI to cite this document:: 10.5283/epub.51960

Hardardottir, Lilja ; Bazzano, Maria Victoria ; Glau, Laura ; Gattinoni, Luca ; Köninger, Angela ; Tolosa, Eva ; Solano, Maria Emilia

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Date of publication of this fulltext: 21 Mar 2022 14:39

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Abstract

CD8+ T cells are the most frequent T cell population in the immune cell compartment at the feto-maternal interface. Due to their cytotoxic potential, the presence of CD8+ T cells in the immune privileged pregnant uterus has raised considerable interest. Here, we review our current understanding of CD8+ T cell biology in the uterus of pregnant women and discuss this knowledge in relation to a ...