Impact of Myeloid p38α/MAPK on Orthodontic Tooth Movement

URN to cite this document:: urn:nbn:de:bvb:355-epub-520550
DOI to cite this document:: 10.5283/epub.52055

Kirschneck, Christian

; Nusser, Hendrik ; Jantsch, Jonathan ; Proff, Peter ; Schröder, Agnes

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Date of publication of this fulltext: 05 Apr 2022 05:00

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Abstract

Objectives: Myeloid p38 alpha/MAPK regulate and coordinate osteoclastogenesis. The present study was conducted to investigate the role of myeloid p38 alpha/MAPK during orthodontic tooth movement. Methods: Orthodontic tooth movement was performed in wildtype and p38 alpha(Delta myel) mice lacking p38 alpha/MAPK expression in myeloid cells. First, bone parameter as well as osteoblast and osteoclast ...