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Effects of Atrial Fibrillation on the Human Ventricle

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Pabel, Steffen ; Knierim, Maria ; Stehle, Thea ; Alebrand, Felix ; Paulus, Michael ; Sieme, Marcel ; Herwig, Melissa ; Barsch, Friedrich ; Körtl, Thomas ; Pöppl, Arnold ; Wenner, Brisca ; Ljubojevic-Holzer, Senka ; Molina, Cristina E. ; Dybkova, Nataliya ; Camboni, Daniele ; Fischer, Thomas H. ; Sedej, Simon ; Scherr, Daniel ; Schmid, Christof ; Brochhausen, Christoph ; Hasenfuß, Gerd ; Maier, Lars S. ; Hamdani, Nazha ; Streckfuss-Bömeke, Katrin ; Sossalla, Samuel
Date of publication of this fulltext: 07 Apr 2022 04:45


Rationale: Atrial fibrillation (AF) and heart failure often coexist, but their interaction is poorly understood. Clinical data indicate that the arrhythmic component of AF may contribute to left ventricular (LV) dysfunction. Objective: This study investigates the effects and molecular mechanisms of AF on the human LV. Methods and Results: Ventricular myocardium from patients with aortic stenosis ...


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