Go to content
UR Home

Prolyl‐4‐hydroxylases 2 and 3 control erythropoietin production in renin‐expressing cells of mouse kidneys

URN to cite this document:
urn:nbn:de:bvb:355-epub-521324
DOI to cite this document:
10.5283/epub.52132
Broeker, Katharina A. E. ; Fuchs, Michaela A. A. ; Schrankl, Julia ; Lehrmann, Claudia ; Schley, Gunnar ; Todorov, Vladimir T. ; Hugo, Christian ; Wagner, Charlotte ; Kurtz, Armin

This is the latest version of this item.

[img]
Preview
License: Creative Commons Attribution Non-commercial No Derivatives 4.0
PDF - Published Version
published version with page numbers
(9MB)
Date of publication of this fulltext: 07 Apr 2022 12:17


Abstract

Activation of the hypoxia-signalling pathway induced by deletion of the ubiquitin-ligase von Hippel–Lindau protein causes an endocrine shift of renin-producing cells to erythropoietin (EPO)-expressing cells. However, the underlying mechanisms have not yet been investigated. Since oxygen-regulated stability of hypoxia-inducible transcription factors relevant for EPO expression is dependent on the ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 4239

Dissertations: dissertationen@ur.de
0941 943 3904

Research data: daten@ur.de
0941 943 4239

Contact persons