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Transcriptomic Stress Response in Streptococcus mutans following Treatment with a Sublethal Concentration of Chlorhexidine Digluconate

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Muehler, Denise ; Mao, Xiaojun ; Czemmel, Stefan ; Geißert, Janina ; Engesser, Christina ; Hiller, Karl-Anton ; Widbiller, Matthias ; Maisch, Tim ; Buchalla, Wolfgang ; Al-Ahmad, Ali ; Cieplik, Fabian
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 26 Apr 2022 15:12


Despite the widespread use of antiseptics such as chlorhexidine digluconate (CHX) in dental practice and oral care, the risks of potential resistance toward these antimicrobial compounds in oral bacteria have only been highlighted very recently. Since the molecular mechanisms behind antiseptic resistance or adaptation are not entirely clear and the bacterial stress response has not been ...


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