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Expression of SLC26A9 in Airways and Its Potential Role in Asthma

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Ousingsawat, Jiraporn ; Centeio, Raquel ; Schreiber, Rainer ; Kunzelmann, Karl
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 26 Apr 2022 15:17


SLC26A9 is an epithelial anion transporter with a poorly defined function in airways. It is assumed to contribute to airway chloride secretion and airway surface hydration. However, immunohistochemistry showing precise localization of SLC26A9 in airways is missing. Some studies report localization near tight junctions, which is difficult to reconcile with a chloride secretory function of SLC26A9. ...


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