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Flexible and multifaceted: the plasticity of renin-expressing cells

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Broeker, Katharina A. E. ; Schrankl, Julia ; Fuchs, Michaela A. A. ; Kurtz, Armin
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 24 May 2022 06:32

This publication is part of the DEAL contract with Springer.


The protease renin, the key enzyme of the renin–angiotensin–aldosterone system, is mainly produced and secreted by juxtaglomerular cells in the kidney, which are located in the walls of the afferent arterioles at their entrance into the glomeruli. When the body’s demand for renin rises, the renin production capacity of the kidneys commonly increases by induction of renin expression in vascular ...


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