Flexible and multifaceted: the plasticity of renin-expressing cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-522577
DOI to cite this document:: 10.5283/epub.52257

Broeker, Katharina A. E.

; Schrankl, Julia ; Fuchs, Michaela A. A.

; Kurtz, Armin

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Date of publication of this fulltext: 24 May 2022 06:32

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Abstract

The protease renin, the key enzyme of the renin–angiotensin–aldosterone system, is mainly produced and secreted by juxtaglomerular cells in the kidney, which are located in the walls of the afferent arterioles at their entrance into the glomeruli. When the body’s demand for renin rises, the renin production capacity of the kidneys commonly increases by induction of renin expression in vascular ...