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Phenotypic Adaptation to Antiseptics and Effects on Biofilm Formation Capacity and Antibiotic Resistance in Clinical Isolates of Early Colonizers in Dental Plaque

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Auer, David L. ; Mao, Xiaojun ; Anderson, Annette Carola ; Muehler, Denise ; Wittmer, Annette ; von Ohle, Christiane ; Wolff, Diana ; Frese, Cornelia ; Hiller, Karl-Anton ; Maisch, Tim ; Buchalla, Wolfgang ; Hellwig, Elmar ; Al-Ahmad, Ali ; Cieplik, Fabian
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 14 Jul 2022 07:41


Despite the wide-spread use of antiseptics in dental practice and oral care products, there is little public awareness of potential risks associated with antiseptic resistance and potentially concomitant cross-resistance. Therefore, the aim of this study was to investigate potential phenotypic adaptation in 177 clinical isolates of early colonizers of dental plaque (Streptococcus, Actinomyces, ...


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