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Identification and Isolation of Type II NKT Cell Subsets in Human Blood and Liver

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Yang Zhou, Jordi ; Werner, Jens M. ; Glehr, Gunther ; Geissler, Edward K. ; Hutchinson, James A. ; Kronenberg, Katharina
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 27 Oct 2022 20:53


Background: Steatotic livers are more prone to rejection, but are often transplanted owing to the shortage of available organs. Type II NKT (T2NKT) cells are liver-resident lymphocytes that react to lipids presented by CD1d. The role of T2NKT cells in rejection of fatty liver transplants is unclear, partly because of a lack of T2NKT cell markers and their very low frequency in blood. Here, we ...


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