Identification and Isolation of Type II NKT Cell Subsets in Human Blood and Liver

URN to cite this document:: urn:nbn:de:bvb:355-epub-526045
DOI to cite this document:: 10.5283/epub.52604

Yang Zhou, Jordi ; Werner, Jens M.

; Glehr, Gunther

; Geissler, Edward K. ; Hutchinson, James A. ; Kronenberg, Katharina

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Date of publication of this fulltext: 27 Oct 2022 20:53

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Abstract

Background: Steatotic livers are more prone to rejection, but are often transplanted owing to the shortage of available organs. Type II NKT (T2NKT) cells are liver-resident lymphocytes that react to lipids presented by CD1d. The role of T2NKT cells in rejection of fatty liver transplants is unclear, partly because of a lack of T2NKT cell markers and their very low frequency in blood. Here, we ...