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Ecological Effects of Daily Antiseptic Treatment on Microbial Composition of Saliva-Grown Microcosm Biofilms and Selection of Resistant Phenotypes

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Mao, Xiaojun ; Hiergeist, Andreas ; Auer, David L ; Scholz, Konstantin J. ; Muehler, Denise ; Hiller, Karl-Anton ; Maisch, Tim ; Buchalla, Wolfgang ; Hellwig, Elmar ; Gessner, André ; Al-Ahmad, Ali ; Cieplik, Fabian
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 14 Jul 2022 08:06


Antiseptics are widely used in dental practice and included in numerous over-the-counter oral care products. However, the effects of routine antiseptic use on microbial composition of oral biofilms and on the emergence of resistant phenotypes remain unclear. Microcosm biofilms were inoculated from saliva samples of four donors and cultured in the Amsterdam Active Attachment biofilm model for 3 ...


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