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Photochromic Fentanyl Derivatives for Controlled μ-Opioid Receptor Activation

URN to cite this document:
urn:nbn:de:bvb:355-epub-527062
DOI to cite this document:
10.5283/epub.52706
Lahmy, Ranit ; Hübner, Harald ; Schmidt, Maximilian F. ; Lachmann, Daniel ; Gmeiner, Peter ; König, Burkhard
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Date of publication of this fulltext: 05 Aug 2022 04:26


Abstract

Photoswitchable ligands as biological tools provide an opportunity to explore the kinetics and dynamics of the clinically relevant µ-opioid receptor. These ligands can potentially activate and deactivate the receptor when desired, using light. Spatial and temporal control of biological activity allows for application in a diverse range of biological investigations. Photoswitchable ligands have ...

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