Apheresis for chimeric antigen receptor T‐cell production in adult lymphoma patients

URN to cite this document:: urn:nbn:de:bvb:355-epub-527311
DOI to cite this document:: 10.5283/epub.52731

Harrer, Dennis Christoph ; Heidenreich, Martin ; Fante, Matthias Alexander ; Müller, Viktoria ; Hähnel, Viola ; Offner, Robert ; Burkhardt, Ralph

; Herr, Wolfgang ; Edinger, Matthias ; Wolff, Daniel ; Thomas, Simone ; Brosig, Andreas

License: Creative Commons Attribution Non-commercial No Derivatives 4.0
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Date of publication of this fulltext: 09 Aug 2022 04:50

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Abstract

Background To date, in-depth analysis of leukapheresis products as starting material for CAR T-cell manufacturing, specifically Tisagenlecleucel production, are scarce. In this study, we report on lymphapheresis data for production of Tisagenlecleucel for elderly and pretreated lymphoma patients. Study Design and Methods Spectra Optia from Terumo BCT, Lakewood, CO, was employed for apheresis ...