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Loss of MMP-27 Predicts Mandibular Bone Invasion in Oral Squamous Cell Carcinoma

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Eichberger, Jonas ; Weber, Florian ; Spanier, Gerrit ; Gerken, Michael ; Schreml, Stephan ; Schulz, Daniela ; Fiedler, Mathias ; Ludwig, Nils ; Bauer, Richard J. ; Reichert, Torsten E. ; Ettl, Tobias
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 09 Sep 2022 13:03


Invasion of the mandibular bone is frequent in oral squamous cell carcinoma (OSCC), which often results in extensive ablative and reconstructive procedures for the patient. The purpose of this single-center, retrospective study was to identify and evaluate potential biomarkers and risk factors for bone invasion in OSCC. Initially, in silico gene expression analysis was performed for different ...


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