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Can Gene Expression Analysis in Zero-Time Biopsies Predict Kidney Transplant Rejection?

URN to cite this document:
urn:nbn:de:bvb:355-epub-528360
DOI to cite this document:
10.5283/epub.52836
Vonbrunn, Eva ; Angeloni, Miriam ; Büttner-Herold, Maike ; Müller-Deile, Janina ; Heller, Katharina ; Bleich, Erik ; Söllner, Stefan ; Amann, Kerstin ; Ferrazzi, Fulvia ; Daniel, Christoph
[img]License: Creative Commons Attribution 4.0
PDF - Published Version
(9MB)
Date of publication of this fulltext: 31 Aug 2022 16:05


Abstract

Zero-time biopsies are taken to determine the quality of the donor organ at the time of transplantation. Histological analyses alone have so far not been able to identify parameters that allow the prediction of subsequent rejection episodes or graft survival. This study investigated whether gene expression analyses of zero-time biopsies might support this prediction. Using a well-characterized ...

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