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Can Gene Expression Analysis in Zero-Time Biopsies Predict Kidney Transplant Rejection?

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Vonbrunn, Eva ; Angeloni, Miriam ; Büttner-Herold, Maike ; Müller-Deile, Janina ; Heller, Katharina ; Bleich, Erik ; Söllner, Stefan ; Amann, Kerstin ; Ferrazzi, Fulvia ; Daniel, Christoph
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Date of publication of this fulltext: 31 Aug 2022 16:05


Zero-time biopsies are taken to determine the quality of the donor organ at the time of transplantation. Histological analyses alone have so far not been able to identify parameters that allow the prediction of subsequent rejection episodes or graft survival. This study investigated whether gene expression analyses of zero-time biopsies might support this prediction. Using a well-characterized ...


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