Action of the Photochrome Glyght on GABAergic Synaptic Transmission in Mouse Brain Slices

URN to cite this document:: urn:nbn:de:bvb:355-epub-528896
DOI to cite this document:: 10.5283/epub.52889

Petukhova, Elena

; Ponomareva, Daria ; Rustler, Karin ; König, Burkhard ; Bregestovski, Piotr

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 20 Sep 2022 08:15

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Abstract

Glyght is a new photochromic compound described as an effective modulator of glycine receptors at heterologous expression, in brain slices and in zebrafish larvae. Glyght also caused weak inhibition of GABA(A)-mediated currents in a cell line expressing alpha 1/beta 2/gamma 2 GABA(A) receptors. However, the effects of Glyght on GABAergic transmission in the brain have not been analysed, which ...