Go to content
UR Home

Effect of the human endotoxin challenge on tedizolid tissue penetration

Jorda, Anselm ; Wulkersdorfer, Beatrix ; Schoergenhofer, Christian ; Matzneller, Peter ; Jalali, Valentin A. L. ; Bauer, Martin ; Wölfl‐Duchek, Michael ; Lackner, Edith ; Dorn, Christoph ; Jilma, Bernd ; Zeitlinger, Markus



Abstract

The effects of the human endotoxin challenge on tissue pharmacokinetics are unknown. In the present study, we aimed to assess the effect of the endotoxin challenge on interstitial fluid pharmacokinetics of tedizolid in healthy volunteers using intramuscular microdialysis. Eight healthy male subjects were treated with 200 mg of tedizolid phosphate for 6 days. On day 6, an intravenous bolus of LPS ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons