Vaginal Delivery Is Associated with Neurochemical Evidence of Increased Neuroaxonal Remodelling in Infants from the KUNO-Kids Health Study: Cross-Sectional Analysis

URN to cite this document:: urn:nbn:de:bvb:355-epub-530882
DOI to cite this document:: 10.5283/epub.53088

Kürner, Katja ; Goeral, Katharina ; Atkinson, Andrew ; Brandstetter, Susanne

; Toncheva, Antoaneta A.

; Kabesch, Michael

; Apfelbacher, Christian J.

; Melter, Michael

; Seelbach-Göbel, Birgit ; Berger, Angelika ; Kuhle, Jens ; Wellmann, Sven

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 21 Oct 2022 06:22

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Abstract

Aim: Little is known about neonatal brain plasticity or the impact of birth mode on neurointegrity. As a reflection of neuroaxonal damage, the neuronal structural protein neurofilament light chain (NfL) has emerged as a highly specific biomarker. Our purpose was to test the hypothesis that vaginal delivery is associated with increased NfL in neonates. Methods: NfL concentrations were measured ...